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Written by David Stephen Kozin   
Sunday, 19 August 2007

 

SECOND MANUSCRIPT PUBLISHED IN THE JOURNAL OF CLINICAL PSYCHIATRY

 

Simeon, D., Kozin, D. S., Segal, K., & Lerch, B. (2009). Is depersonalization disorder initiated by illicit drug use any different? a survey of 394 adults. The Journal of Clinical Psychiatry,2009;70(10):1358–1364 doi:10.4088/JCP.08m04370) 

 

NODID'S RESEARCH WAS PRESENTED AT THIS YEAR'S INTERNATIONAL SOCIETY FOR THE STUDY OF TRAUMA AND DISSOCIATION'S CONFERENCE IN CHICAGO

 

 

Abstract: Previous stud ies have documented that in a substantial minority of individuals with depersonalization disorder, onset is first triggered by drug ingestion. The goal of this study was to systematically compare a large sample of drug (D) versus non-drug (ND) initiated chronic depersonalization. We conducted an internet survey of 394 adults endorsing depersonalization and / or derealization as defined in the DSM-IV-TR. Sixty-four questions inquired about demographic and clinical characteristics, illness course, substance use histories, and treatment response. The Cambridge Depersonalization Scale (CDS) was administered. Compared to ND group (N = 198), the D group (N = 196) comprised of more male and younger individuals. The two most common precipitating drugs were cannabis and hallucinogens, followed by ecstasy, then ketamine. Comparison of the D and ND groups revealed similar illness course, impairment, suicidality, and limited treatment efficacy. The D group showed greater spontaneous improvement over time, statistically significant but not clinically robust. The groups did not differ in total CDS score or on the four subscale scores of unreality of self, perceptual alterations, unreality of surroundings, and temporal disintegration. Numbing was greater in the ND group only prior to controlling for age and gender The study documents the chronicity and morbidity of the depersonalization syndrome initiated by substance use, as well as the uniform phenotype of the syndrome regardless of antecedent.

 

NODID'S FIRST PUBLICATION IS AVAILABLE

Daphne Simeon, David Stephen Kozin, Karina Segal, Brenna Lerch, Roxanne Dujour and Timo Giesbrech De-constructing depersonalization: Further evidence for symptom clusters, Psychiatry Research, Volume 157, Issues 1-3, 15 January 2008, Pages 303-306

 

 

 

 

 

 

 

 

 

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Last Updated ( Wednesday, 20 January 2010 )